【PET/CT检查安全吗?】

时间:2015-08-10

 

大型医疗设备正电子发射断层显像/x线断层显像仪(Positron Emission Tomography /Computed Tomography, PET/CT)检查在肿瘤的早期诊断和鉴别诊断;肿瘤的分期和再分期、分化程度;肿瘤复发的鉴别;肿瘤的治疗方案的指导;肿瘤治疗疗效评价;肿瘤预后的评估;血肿瘤标志物持续增高、肿瘤家族等肿瘤高危者的肿瘤原发和转移灶的寻找等方面,以及神经精神疾病、心血管疾病的诊疗评估等方面均具有很好的优势,对于有适应症患者接受PET/CT检查的受益明显大于极低概率的辐射风险,甚至使受检者获得挽救生命的机会。

然而,随着PET/CT的应用推广,越来越多的人开始接触和接受PET/CT检查。随着媒体对辐射安全知识的扩大宣传,接受PET/CT检查的患者开始担忧PET/CT的辐射安全,甚至医务人员也惧怕PET/CT检查,到底PET/CT检查安全吗?患者检查后医务人员多久可对患者进行医疗活动?下面全民体检网 www.qmtj.net 为大家分享专家就此两方面疑问分别释疑。

一、PET/CT检查安全吗?

PET/CT的辐射剂量来源来源于放射性核素和X-CT两部分,其中,PET使用的放射性辐射绝大多数来源于氟-18(18F),18F发射正电子,产生高能γ射线, 辐射剂量约为2.1×10-2mSv/MBq,新型PET/CT使用的放射性药物剂量减少了一般,一次检查患者接受的辐射剂量大概3.9mSV左右。第二部分辐射剂量的主要来源于CT扫描,高端PET/CT多配置智能低剂量CT,智能低剂量扫描的辐射剂量大大降低,全身PET/CT检查的总辐射剂量一般在15mSv左右,低于常规局部增强CT扫描的辐射剂量。

一次性接受50mSv以下的辐射剂量是安全的,超过100mSv才有可能产生直接辐射损伤的风险(存在辐射确定性效应的风险),达到250mSv辐射剂量为亚临床剂量(无症状性过量辐射,有可能造成少量生物细胞损伤,人体可修复或代偿,不至于产生临床症状),超过500mSv辐射照射,则可能造成5%受照人员出现辐射损伤症状,超过1000mSv辐射照射,才可能造成25%受照人员出现辐射损伤症状。而PET/CT检查的辐射剂量均远远低于上述安全剂量,是非常安全的医学检查。

二、PET/CT检查后医务人员多久可接触患者?

PET/CT受检者对周围人群的辐射主要来源于放射性药物,由于其有效半衰期短,体内放射药物很快排泄和衰变下降到安全水平。一般注射药物后需要等待1小时后检查,加上其他准备时间及延迟显像,患者离开核医学科时一般需要2小时以上。目前新型PET/CT检查一般使用185MBq氟-18标记的药物,2小时后患者体内放射性核素大多已衰变和排泄,对周围1米人群的辐射剂量已下降到0.01mSv/h以下,随时间推移患者体内的放射性药物进一步衰变减少,所产生的辐射剂量更低。例如,患者检查完后离开核医学时,医务人员此时接触患者进行30分钟医疗活动,可能接受的辐射剂量大约只有0.005mSv(5μSv)。我们知道10km高空的天然辐射剂量大概为 5μSv/h,接受5μSv的辐射剂量相当于您坐1小时飞机所接受的辐射剂量,基本可忽略不计。也就是说,患者检查完PET/CT后离开核医学科后,患者体内的放射性药物对周围所产生辐射剂量已下降到天然高空的本底水平,此时医务人员对受检患者的正常医疗活动,医务人员接受辐射剂量基本可以忽略不计。

总之, PET/CT检查需要掌握好适应症,采用正当化原则使用PET/CT检查,帮助医师解决临床诊疗中的问题,可使受检者获益。我院安装的新一代PET/CT由于PET灵敏度提高了,使用放射性药物减少了;同时CT配备了智能低剂量扫描技术,使得PET/CT检查的辐射剂量更低更安全了。PET/CT检查的辐射剂量均远远低于辐射安全剂量,是非常安全的医学检查,患者检查后对医务人员的辐射剂量更低,低于高空天然辐射本底水平,基本可忽略不计。

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